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乔欢欢

职称/职务:副研究员
办公室:天津大学10号教学楼207室
邮箱:qiaohh@tju.edu.cn

个人简介

乔欢欢,博士,副研究员,硕士生导师。2019年博士毕业于清华大学生命科学学院。在Nature Communications等国内外期刊共发表论文17篇,其中通讯/一作/共一发表高质量论文7篇(SCI一区1篇,二区2篇)。主持中国博士后基金面上项目1项和校级科研项目2项;作为合作负责人,主持天津市医工结合专项重点项目1项;参与国家级科研项目3项。


主要研究方向

研究方向为基因编辑技术,肿瘤治疗,纳米医学。


代表性学术成果

论文:

[1] Huan Huan Qiao#; Fang Wang; Rong Gang Xu; Jin Sun; Ruibao Zhu; Decai Mao; Xingjie Ren; Xia Wang; Yu Jia; Ping Peng; Da Shen; Lu Ping Liu; Zhijie Chang; Guirong Wang; Shao Li; Jun Yuan Ji; Qingfei Liu; Jian Quan Ni. An efficient and multiple target transgenic RNAi technique with low toxicity in Drosophila. Nature Communications, 2018.10, 9(1): 0~4160.

[2] Wang Yiwen, Tian Xiaohan, Zhu Chunfeng, Yu Xiaoyu, Miao Yaodong, Qiao Huanhuan*. Genetics of metallothioneins in Drosophila melanogaster. Chemosphere; 288(Pt 2):132562.

[3] Huanhuan Qiao#, Jieting Wu, Xiaodong Zhang, Jian Luo, Hao Wang*, Dong Ming*. The Advance of CRISPR-Cas9-Based and NIR/CRISPR-Cas9-Based Imaging System. Frontiers in Chemistry. https://doi.org/10.3389/fchem.2021.786354.

[4] Zhihao Yang#, Jin Sun#, Yuzhao Hu#, Fang Wang#, Xia Wang#, Huan-Huan Qiao#, Jiang Xu, Decai Mao, Xingjie Ren, Li-Xia Pan, Rong-Gang Xu, BoWen Xu, Yifan Zhang, Haiyi Li, Wei Miao, Yanhui Hu, Zhijie Chang, Dong Wang, Jian-Quan Ni*; Histone H1 defect in escort cells triggers germline tumor in Drosophila ovary; Developmental Biology; 424 (2017); 2017.4.1; 40–49.

[5] Xingjie Ren#, Zhihao Yang#, Decai Mao#, Zai Chang#, Huan-Huan Qiao#, Xia Wang#, Jin Sun, Qun Hu, Yan Cui, Lu-Ping Liu, Jun-Yuan Ji, Jiang Xu* and Jian-Quan Ni*; Performance of the Cas9 Nickase System in Drosophila melanogaster; 4(10); 2014.10.1; 1955-1962.

[6] Fang Wang#, Huan-Huan Qiao#, Rong-Gang Xu, Jin Sun, Ruibao Zhu, Decai Mao, Jian-Quan Ni*. pNP Transgenic RNAi System Manual in Drosophila. Bio Protoc. 2019 5;9(3):e3158.

[7] Ren Xingjie; Yang Zhihao; Xu Jiang; Sun Jin; Mao Decai; Hu Yanhui; Yang Su Juan; Qiao Huan Huan#; Wang Xia; Hu Qun; Deng Patricia; Liu Lu Ping; Ji Jun Yuan; Li Jin Billy; Ni Jian Quan. Enhanced Specificity and Efficiency of the CRISPR/Cas9 System with Optimized sgRNA Parameters in Drosophila. Cell Reports, 2014.11.6, 9(3): 1151~1162

 

科研项目

2019.11-2022.12,中国博士后基金面上项目,CRISPR/Cas9多基因靶向治疗脑胶质瘤的纳米胶束的开发,8万元,负责人。

2021.01-2023.12,天津市医工结合专项重点项目,家族性脑海绵状血管瘤CCM2突变模型构建及氧化应激研究,20万,合作负责人。

2021.01-2021.12,校内自主基金,MSCs调控M1/M2-Th17/Treg免疫稳态进而缓解TBI后炎症反应的机制研究,5万元,负责人。

2020.01-2021.12,校内自主基金,面向新冠肺炎呼吸与运动机能改善的联合电刺激调控方法研究,5万元,负责人。